Skin Solutions Hydroquinone Cream, a tyrosinase inhibitor, in a 8% strength can be used safely twice daily for up to 4 months to treat hyperpigmentation. The efficacy of this treatment is enhanced with 1.0% retinoid which has been compounded in this cream. This combination is often called a "peel and bleach" cream because it both reduces melanin production and speeds up the renewal of skin cells through exfoliation. Similar to a chemical peel, the ingredients remove the top layer of skin to allow undamaged cells to grow. By inhibiting melanin synthesis in the skin, the key factor in bringing dark skin spots to the surface, this medical-grade product fades the appearance of hyperpigmentation, sun spots, age spots, liver spots and freckles by up to seven shades. Instructions included.